BDBM50105772 6-(4-chlorophenyl)-19-(2-methylallyl)-(2S,10R)-11-oxa-8,19-diazahexacyclo[10.9.1.01,10.02,18.04,9.016,22]docosa-4(9),5,7,12,14,16(22)-hexaene-2,13-diol::CHEMBL317536::Naltrindole analogue

SMILES CC(=C)CN1CCC23[C@H]4Oc5c2c(CC1[C@]3(O)Cc1cc(cnc41)-c1ccc(Cl)cc1)ccc5O

InChI Key

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50105772   

TargetDelta-type opioid receptor(Rat)
University of Medicine & Dentistry of New Jersey-Robert Wood Johnson Medical School (Umdnj-Rwjms)

Curated by ChEMBL
LigandPNGBDBM50105772(Naltrindole analogue | 6-(4-chlorophenyl)-19-(2-me...)
Affinity DataKi:  16nMAssay Description:Binding affinity against Opioid receptor delta 1 from rat brain membranes using [3H]DADLEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2014
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50105772(Naltrindole analogue | 6-(4-chlorophenyl)-19-(2-me...)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]DADLE from Opioid receptor delta 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50105772(Naltrindole analogue | 6-(4-chlorophenyl)-19-(2-me...)
Affinity DataKi:  300nMAssay Description:Displacement of [3H]U-69593 from Opioid receptor kappa 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
University of Medicine & Dentistry of New Jersey-Robert Wood Johnson Medical School (Umdnj-Rwjms)

Curated by ChEMBL
LigandPNGBDBM50105772(Naltrindole analogue | 6-(4-chlorophenyl)-19-(2-me...)
Affinity DataKi:  302nMAssay Description:Binding affinity against Opioid receptor kappa 1 from guinea pig brain membranes using [3H]U-69593More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2014
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50105772(Naltrindole analogue | 6-(4-chlorophenyl)-19-(2-me...)
Affinity DataKi: >6.00E+3nMAssay Description:Displacement of [3H]DAMGO from Opioid receptor mu 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed