BDBM50105778 12-methoxy-18-(2-methylallyl)-(2S,9R)-10-oxa-6,7,18-triazahexacyclo[9.9.1.01,9.02,17.04,8.015,21]henicosa-4(8),5,11,13,15(21)-pentaen-2-ol::CHEMBL95847::Naltrindole analogue

SMILES COc1ccc2CC3N(CC(C)=C)CCC45[C@@H](Oc1c24)c1[nH]ncc1C[C@@]35O

InChI Key

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50105778   

TargetDelta-type opioid receptor(Rat)
University of Medicine & Dentistry of New Jersey-Robert Wood Johnson Medical School (Umdnj-Rwjms)

Curated by ChEMBL
LigandPNGBDBM50105778(Naltrindole analogue | 12-methoxy-18-(2-methylally...)
Affinity DataKi:  2.40E+3nMAssay Description:Binding affinity against Opioid receptor delta 1 from rat brain membranes using [3H]DADLEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2014
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50105778(Naltrindole analogue | 12-methoxy-18-(2-methylally...)
Affinity DataKi:  2.40E+3nMAssay Description:Displacement of [3H]DADLE from Opioid receptor delta 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
University of Medicine & Dentistry of New Jersey-Robert Wood Johnson Medical School (Umdnj-Rwjms)

Curated by ChEMBL
LigandPNGBDBM50105778(Naltrindole analogue | 12-methoxy-18-(2-methylally...)
Affinity DataKi:  3.09E+3nMAssay Description:Binding affinity against Opioid receptor kappa 1 from guinea pig brain membranes using [3H]U-69593More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2014
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50105778(Naltrindole analogue | 12-methoxy-18-(2-methylally...)
Affinity DataKi:  3.10E+3nMAssay Description:Displacement of [3H]U-69593 from Opioid receptor kappa 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50105778(Naltrindole analogue | 12-methoxy-18-(2-methylally...)
Affinity DataKi: >6.00E+3nMAssay Description:Displacement of [3H]DAMGO from Opioid receptor mu 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed