BDBM50105893 9-(3-Guanidino-propyl)-15-(3H-imidazol-4-ylmethyl)-6-(1H-indol-3-ylmethyl)-12-naphthalen-2-ylmethyl-5,8,11,14,17,20-hexaoxo-1,4,7,10,13,16hexaaza-cycloicosane-3-carboxylic acid::CHEMBL434985

SMILES NC(=N)NCCC[C@@H]1NC(=O)[C@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CCC(=O)NCC(NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC1=O)C(N)=O

InChI Key InChIKey=UTARRQKZBUCQBR-ISPDCEQMSA-N

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50105893   

TargetMelanocortin receptor 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50105893(9-(3-Guanidino-propyl)-15-(3H-imidazol-4-ylmethyl)...)
Affinity DataKi:  0.260nMAssay Description:Binding affinity against human melanocortin receptor 4 (hMC4R) (concentration of the peptide at 50% specific binding)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50105893(9-(3-Guanidino-propyl)-15-(3H-imidazol-4-ylmethyl)...)
Affinity DataKi:  29nMAssay Description:Binding affinity against human melanocortin receptor 3 (hMC3R) (concentration of the peptide at 50% specific binding)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50105893(9-(3-Guanidino-propyl)-15-(3H-imidazol-4-ylmethyl)...)
Affinity DataKi:  65nMAssay Description:Binding affinity against human melanocortin receptor 5 (hMC5R) (concentration of the peptide at 50% specific binding)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50105893(9-(3-Guanidino-propyl)-15-(3H-imidazol-4-ylmethyl)...)
Affinity DataEC50:  210nMAssay Description:Increase in intracellular cAMP in CHO cells expressing human melanocortin receptor 5.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed