BDBM50106711 5-[2-[1-(3,5-Bis-trifluoromethyl-phenyl)-ethoxy]-3-(4-fluoro-phenyl)-morpholin-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL135613::MK-869

SMILES C[C@@H](OC1OCCN(Cc2n[nH]c(=O)[nH]2)[C@H]1c1ccc(F)cc1)c1cc(cc(c1)C(F)(F)F)C(F)(F)F

InChI Key InChIKey=ATALOFNDEOCMKK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50106711   

TargetSubstance-P receptor(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50106711(5-[2-[1-(3,5-Bis-trifluoromethyl-phenyl)-ethoxy]-3...)
Affinity DataIC50: 0.0900nMAssay Description:In vitro inhibition of binding of [125I]-substance P to tachykinin receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed