BDBM50108802 3,11-difluoro-6,8,13-trimethyl-8H-quino[4,3,2-kl]acridin-13-ium; methyl sulfate(RHPS4)::CHEMBL158083::RHPS4

SMILES Cc1cc2n(C)c3ccc(F)cc3c3[n+](C)c4ccc(F)cc4c(c1)c23

InChI Key InChIKey=FJUYVGXXNUNWDT-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50108802   

TargetTelomerase reverse transcriptase(Homo sapiens (Human))TBA
LigandPNGBDBM50108802(3,11-difluoro-6,8,13-trimethyl-8H-quino[4,3,2-kl]a...)
Affinity DataIC50:  3.31E+8nMAssay Description:Inhibition of Homo sapiens (human) telomerase assessed as formation of G-tetraplexes by gel mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetTelomerase reverse transcriptase(Homo sapiens (Human))TBA
LigandPNGBDBM50108802(3,11-difluoro-6,8,13-trimethyl-8H-quino[4,3,2-kl]a...)
Affinity DataIC50:  330nMAssay Description:Inhibition of telomerase activity using TRAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed