BDBM50110039 1-[2-(3-Cyclopropylmethoxy-4-methoxy-phenyl)-propyl]-1,3-dihydro-imidazol-2-one::CHEMBL434092

SMILES COc1ccc(cc1OCC1CC1)C(C)Cn1cc[nH]c1=O

InChI Key InChIKey=ACBYRQONKZKIIY-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50110039   

LigandPNGBDBM50110039(1-[2-(3-Cyclopropylmethoxy-4-methoxy-phenyl)-propy...)
Affinity DataKi:  3.5nMAssay Description:Displacement of [3H]rolipram from rat forebrain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50110039(1-[2-(3-Cyclopropylmethoxy-4-methoxy-phenyl)-propy...)
Affinity DataIC50:  86nMAssay Description:Inhibitory activity against recombinant phosphodiesterase 4B (PDE4B) of human mononuclear lymphocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed