BDBM50113230 BMS-337197::CHEMBL64830::N-{2-[2-(3-Methoxy-4-oxazol-5-yl-phenylamino)-oxazol-5-yl]-phenyl}-N-methyl-2-morpholin-4-yl-acetamide

SMILES COc1cc(Nc2ncc(o2)-c2ccccc2N(C)C(=O)CN2CCOCC2)ccc1-c1cnco1

InChI Key InChIKey=GLOULEOFVQQCTE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50113230   

TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50113230(BMS-337197 | CHEMBL64830 | N-{2-[2-(3-Methoxy-4-ox...)
Affinity DataIC50:  16nMAssay Description:Inhibitory concentration against Inosine-5'-monophosphate dehydrogenase 2 was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50113230(BMS-337197 | CHEMBL64830 | N-{2-[2-(3-Methoxy-4-ox...)
Affinity DataIC50:  12nMAssay Description:Inhibition of human inosine-5'-monophosphate dehydrogenase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50113230(BMS-337197 | CHEMBL64830 | N-{2-[2-(3-Methoxy-4-ox...)
Affinity DataIC50:  16nMAssay Description:Inhibitory activity tested against inosine-5'-monophosphate dehydrogenase 2 (IMPDH-II) enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50113230(BMS-337197 | CHEMBL64830 | N-{2-[2-(3-Methoxy-4-ox...)
Affinity DataIC50:  16nMAssay Description:Inhibition of inosine-5'-monophosphate dehydrogenase 2.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed