BDBM50113562 (S)-3-(2'-Methoxy-biphenyl-4-yl)-2-{[(R)-2-(pyrrolidine-1-carbonyl)-tetrahydro-furan-2-carbonyl]-amino}-propionic acid::CHEMBL290951

SMILES COc1ccccc1-c1ccc(C[C@H](NC(=O)[C@]2(CCCO2)C(=O)N2CCCC2)C(O)=O)cc1

InChI Key InChIKey=GJFNKTYJRCAGCV-HFZDXXHNSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50113562   

TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50113562((S)-3-(2'-Methoxy-biphenyl-4-yl)-2-{[(R)-2-(pyrrol...)
Affinity DataIC50:  4.40nMAssay Description:Inhibition of alpha4-beta1 (very late) antigen binding with VCAM-1 immunoglobulin plus 5% human plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50113562((S)-3-(2'-Methoxy-biphenyl-4-yl)-2-{[(R)-2-(pyrrol...)
Affinity DataIC50:  23nMAssay Description:Inhibition of alpha4-beta7 antigen with MAdCAM immunoglobulinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50113562((S)-3-(2'-Methoxy-biphenyl-4-yl)-2-{[(R)-2-(pyrrol...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of alpha4-beta1 (very late) antigen binding with VCAM-1 immunoglobulinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed