BDBM50115340 4-(6,7-Dimethoxy-quinazolin-4-yl)-piperazine-1-carboxylic acid (4-chloro-phenyl)-amide::CHEMBL104325

SMILES COc1cc2ncnc(N3CCN(CC3)C(=O)Nc3ccc(Cl)cc3)c2cc1OC

InChI Key InChIKey=BVFYPXLAWPVNTJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50115340   

TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50115340(4-(6,7-Dimethoxy-quinazolin-4-yl)-piperazine-1-car...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of Platelet-derived growth factor receptor beta phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50115340(4-(6,7-Dimethoxy-quinazolin-4-yl)-piperazine-1-car...)
Affinity DataIC50:  1.10E+3nMAssay Description:Concentration required for 50% inhibition against autophosphorylation of Platelet-derived growth factor receptor beta in intact cells using a two sit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50115340(4-(6,7-Dimethoxy-quinazolin-4-yl)-piperazine-1-car...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of platelet-derived growth factor receptor beta phosphorylation was measured in intact cells using a two-site enzyme linked immunosorbent ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed