BDBM50119076 (1R,6S,8S,8aS)-6-Amino-1-ethyl-8-methoxy-6-(2-methyl-allyl)-5-oxo-octahydro-indolizine-3-carboxylic acid 4-carbamimidoyl-benzylamide fumarate

SMILES CC[C@@H]1CC(N2[C@@H]1[C@H](C[C@@](N)(CC(C)=C)C2=O)OC)C(=O)NCc1ccc(cc1)C(N)=N

InChI Key InChIKey=ZDEJXRLDHXDDRW-OXVIHHKKSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50119076   

TargetCoagulation factor XI(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50119076((1R,6S,8S,8aS)-6-Amino-1-ethyl-8-methoxy-6-(2-meth...)
Affinity DataIC50: >1.33E+5nMAssay Description:Compound was tested for inhibitory activity against Coagulation factor XIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50119076((1R,6S,8S,8aS)-6-Amino-1-ethyl-8-methoxy-6-(2-meth...)
Affinity DataIC50:  3.70E+4nMAssay Description:Compound was tested for inhibitory activity against PlasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50119076((1R,6S,8S,8aS)-6-Amino-1-ethyl-8-methoxy-6-(2-meth...)
Affinity DataIC50:  380nMAssay Description:Compound was tested for inhibitory activity against ThrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50119076((1R,6S,8S,8aS)-6-Amino-1-ethyl-8-methoxy-6-(2-meth...)
Affinity DataIC50:  1.60E+3nMAssay Description:Compound was tested for inhibitory activity against Coagulation factor VIIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed