BDBM50119076 (1R,6S,8S,8aS)-6-Amino-1-ethyl-8-methoxy-6-(2-methyl-allyl)-5-oxo-octahydro-indolizine-3-carboxylic acid 4-carbamimidoyl-benzylamide fumarate

SMILES CC[C@@H]1CC(N2[C@@H]1[C@H](C[C@@](N)(CC(C)=C)C2=O)OC)C(=O)NCc1ccc(cc1)C(N)=N

InChI Key InChIKey=ZDEJXRLDHXDDRW-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50119076   

TargetCoagulation factor XI(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50119076((1R,6S,8S,8aS)-6-Amino-1-ethyl-8-methoxy-6-(2-meth...)
Affinity DataIC50: 1.33E+5nMAssay Description:Compound was tested for inhibitory activity against Coagulation factor XIaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed
TargetCoagulation factor VII(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50119076((1R,6S,8S,8aS)-6-Amino-1-ethyl-8-methoxy-6-(2-meth...)
Affinity DataIC50: 1.60E+3nMAssay Description:Compound was tested for inhibitory activity against Coagulation factor VIIaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50119076((1R,6S,8S,8aS)-6-Amino-1-ethyl-8-methoxy-6-(2-meth...)
Affinity DataIC50: 380nMAssay Description:Compound was tested for inhibitory activity against ThrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed
TargetPlasminogen(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50119076((1R,6S,8S,8aS)-6-Amino-1-ethyl-8-methoxy-6-(2-meth...)
Affinity DataIC50: 3.70E+4nMAssay Description:Compound was tested for inhibitory activity against PlasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed