BDBM50120686 (R)-N-hydroxy-2-((S)-3-(4-isobutylphenyl)-3-methyl-2-oxopyrrolidin-1-yl)propanamide::CHEMBL148118::N-Hydroxy-2-[3-(4-isobutyl-phenyl)-3-methyl-2-oxo-pyrrolidin-1-yl]-propionamide

SMILES CC(C)Cc1ccc(cc1)[C@]1(C)CCN([C@H](C)C(=O)NO)C1=O

InChI Key InChIKey=NIUYUCAJYPRIRB-ACJLOTCBSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50120686   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50120686((R)-N-hydroxy-2-((S)-3-(4-isobutylphenyl)-3-methyl...)
Affinity DataKi:  586nMAssay Description:Affinity towards Matrix metalloprotease-9 (MMP-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50120686((R)-N-hydroxy-2-((S)-3-(4-isobutylphenyl)-3-methyl...)
Affinity DataKi:  701nMAssay Description:Affinity for Matrix metalloprotease-2 (MMP-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50120686((R)-N-hydroxy-2-((S)-3-(4-isobutylphenyl)-3-methyl...)
Affinity DataKi:  4.00E+3nMAssay Description:Affinity towards Matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
The M. S. University Of Baroda

Curated by ChEMBL
LigandPNGBDBM50120686((R)-N-hydroxy-2-((S)-3-(4-isobutylphenyl)-3-methyl...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Sus scrofa (pig))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50120686((R)-N-hydroxy-2-((S)-3-(4-isobutylphenyl)-3-methyl...)
Affinity DataIC50:  1.00E+3nMAssay Description:Affinity for Tumor necrosis factor alpha converting enzyme (TACE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed