BDBM50121031 CHEMBL419772::[(S)-2-Methyl-1-((5R,6S)-7-oxo-4-oxa-1-aza-bicyclo[3.2.0]hept-6-ylcarbamoyl)-propyl]-carbamic acid benzyl ester

SMILES CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@H]1[C@H]2OCCN2C1=O

InChI Key InChIKey=OEGLOMHKABJFTM-JJRVBVJISA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50121031   

TargetCathepsin S(Human)
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121031(CHEMBL419772 | [(S)-2-Methyl-1-((5R,6S)-7-oxo-4-ox...)
Affinity DataIC50:  260nMAssay Description:In vitro Inhibitory activity of the compound was determined against Cathepsin S cysteine protease by using Cbz-Val-Arg-AMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Human)
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121031(CHEMBL419772 | [(S)-2-Methyl-1-((5R,6S)-7-oxo-4-ox...)
Affinity DataIC50:  100nMAssay Description:In vitro Inhibitory activity of the compound was determined against Cathepsin K cysteine protease by using Cbz-Phe-Arg-AMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Human)
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121031(CHEMBL419772 | [(S)-2-Methyl-1-((5R,6S)-7-oxo-4-ox...)
Affinity DataIC50:  3.00E+4nMAssay Description:In vitro Inhibitory activity of the compound was determined against Cathepsin B cysteine protease by using Cbz-Phe-Arg-AMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Rat)
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121031(CHEMBL419772 | [(S)-2-Methyl-1-((5R,6S)-7-oxo-4-ox...)
Affinity DataIC50:  600nMAssay Description:In vitro Inhibitory activity of the compound was determined against Cathepsin L cysteine protease by using Cbz-Phe-Arg-AMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed