BDBM50121422 CHEMBL119869::Lithium; 2-(2,4-dichloro-benzoylamino)-5-(thiophen-2-ylmethoxy)-benzoate

SMILES [O-]C(=O)c1cc(OCc2cccs2)ccc1NC(=O)c1ccc(Cl)cc1Cl

InChI Key InChIKey=RHNGSZQNJSTEEB-UHFFFAOYSA-M

Data  2 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50121422   

TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Biovitrum

Curated by ChEMBL
LigandPNGBDBM50121422(CHEMBL119869 | Lithium; 2-(2,4-dichloro-benzoylami...)
Affinity DataKi:  400nMAssay Description:Ligand binding affinity was determined by displacement of a tritiated tracer by the unlabeled compound to a GST-PPAR fusion protein for Peroxisome pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Biovitrum

Curated by ChEMBL
LigandPNGBDBM50121422(CHEMBL119869 | Lithium; 2-(2,4-dichloro-benzoylami...)
Affinity DataKi:  2.50E+4nMAssay Description:Ligand binding affinity was determined by displacement of a tritiated tracer by the unlabeled compound to a GST-PPAR fusion protein for Peroxisome pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Biovitrum

Curated by ChEMBL
LigandPNGBDBM50121422(CHEMBL119869 | Lithium; 2-(2,4-dichloro-benzoylami...)
Affinity DataEC50:  300nMAssay Description:Transactivation potency was measured by luciferase activity in Caco- 2/TC7 cells transiently co-transfected for the fusion-protein Gal4-PPAR gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Biovitrum

Curated by ChEMBL
LigandPNGBDBM50121422(CHEMBL119869 | Lithium; 2-(2,4-dichloro-benzoylami...)
Affinity DataEC50:  5.00E+3nMAssay Description:Transactivation potency was measured by luciferase activity in Caco- 2/TC7 cells transiently co-transfected for the fusion-protein Gal4-PPAR gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed