BDBM50121892 2-Butyrylamino-1,2,3,4-tetrahydro-naphthalene-2-carboxylic acid ((R)-1-{(S)-1-[(S)-1-(carbamoylmethyl-carbamoyl)-2-(1H-indol-3-yl)-ethylcarbamoyl]-4-guanidino-butylcarbamoyl}-2-phenyl-ethyl)-amide::2-Butyrylamino-1,2,3,4-tetrahydro-naphthalene-2-carboxylic acid (1-{(S)-1-[(S)-1-((S)-carbamoylmethyl-carbamoyl)-2-(1H-indol-3-yl)-ethylcarbamoyl]-4-guanidino-butylcarbamoyl}-2-phenyl-ethyl)-amide::BDBM50451530::CHEMBL2372046

SMILES CCCC(=O)N[C@]1(CCc2ccccc2C1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(N)=O

InChI Key InChIKey=JUVJYZGLTWZLKJ-JPEUWGMBSA-N

Data  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50121892   

TargetMelanocortin receptor 4(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50121892(2-Butyrylamino-1,2,3,4-tetrahydro-naphthalene-2-ca...)
Affinity DataEC50:  290nMAssay Description:Agonist activity against human melanocortin receptor hMC4RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50121892(2-Butyrylamino-1,2,3,4-tetrahydro-naphthalene-2-ca...)
Affinity DataEC50:  4.38E+3nMAssay Description:Agonist activity against human melanocortin receptor hMC1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50121892(2-Butyrylamino-1,2,3,4-tetrahydro-naphthalene-2-ca...)
Affinity DataEC50:  290nMAssay Description:Agonist activity against human melanocortin receptor hMC4RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50121892(2-Butyrylamino-1,2,3,4-tetrahydro-naphthalene-2-ca...)
Affinity DataEC50:  4.40E+3nMAssay Description:Effective concentration required for cAMP accumulation mediated by human Melanocortin 1 receptor in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50121892(2-Butyrylamino-1,2,3,4-tetrahydro-naphthalene-2-ca...)
Affinity DataEC50:  4.38E+3nMAssay Description:Agonist activity against human melanocortin receptor hMC1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50121892(2-Butyrylamino-1,2,3,4-tetrahydro-naphthalene-2-ca...)
Affinity DataEC50:  4.40E+3nMAssay Description:Binding affinity towards human Melanocortin 4 receptor using radiolabeled NDP-MSH displacementMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed