BDBM50123279 19-cyclopropylmethyl-6-(1H-1-pyrrolyl)-11-oxa-8,19-diazahexacyclo[10.9.1.01,10.02,18.04,9.016,22]docosa-4(9),5,7,12,14,16(22)-hexaene-2,13-diol::CHEMBL346165
SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1ncc(cc1C[C@@]35O)-n1cccc1
InChI Key InChIKey=AQPCHMHRVHPFAE-NVSKSXHLSA-N
Data 6 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50123279
Affinity DataKi: 0.400nMAssay Description:Antagonist activity on agonist stimulated [35S]GTP-gamma-S, binding in guinea pig caudate membranes (10 uM SNC-80 as the agonist ligand for delta-rec...More data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Southern Research Institute
Curated by ChEMBL
Southern Research Institute
Curated by ChEMBL
Affinity DataKi: 0.640nMAssay Description:Binding affinity to delta opioid receptor was measured using [3H]DADLEMore data for this Ligand-Target Pair
Affinity DataKi: 4.20nMAssay Description:Antagonist activity on agonist stimulated [35S]GTP-gamma-S, binding in guinea pig caudate membranes (10 uM DAMGO as the agonist ligand for Mu-recepto...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Southern Research Institute
Curated by ChEMBL
Southern Research Institute
Curated by ChEMBL
Affinity DataKi: 8.80nMAssay Description:Antagonist activity on agonist stimulated [35S]GTP-gamma-S, binding in guinea pig caudate membranes (10 uM U69,593 as the agonist ligand for kappa-re...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Southern Research Institute
Curated by ChEMBL
Southern Research Institute
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:Binding affinity for kappa opioid receptor was measured using [3H]U-69593More data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Binding affinity to mu opioid receptor was measured using [3H]DAMGOMore data for this Ligand-Target Pair