BDBM50123759 (E)-(1S,2S,6R,7R)-7-((S)-1-Carbamoyl-2-phenyl-ethylcarbamoyl)-2,6-dihydroxy-1-(4-hydroxy-2,6-dimethyl-benzyl)-8-phenyl-oct-4-enyl-ammonium

SMILES Cc1cc(O)cc(C)c1C[C@H]([NH3+])[C@@H](O)C\C=C\[C@@H](O)[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O

InChI Key InChIKey=MWAQTMFPZSUQRQ-LSANMVLPSA-O

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50123759   

TargetMu-type opioid receptor(Homo sapiens (Human))
Harvard University

Curated by ChEMBL
LigandPNGBDBM50123759((E)-(1S,2S,6R,7R)-7-((S)-1-Carbamoyl-2-phenyl-ethy...)
Affinity DataKi:  0.420nMAssay Description:Displacement of [3H]DAMGO from human Opioid receptor mu 1 expressing CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Harvard University

Curated by ChEMBL
LigandPNGBDBM50123759((E)-(1S,2S,6R,7R)-7-((S)-1-Carbamoyl-2-phenyl-ethy...)
Affinity DataKi:  21nMAssay Description:Displacement of 3H-U-69,593 from Opioid receptor kappa 1 in guinea pig cerebellum preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Harvard University

Curated by ChEMBL
LigandPNGBDBM50123759((E)-(1S,2S,6R,7R)-7-((S)-1-Carbamoyl-2-phenyl-ethy...)
Affinity DataKi:  36nMAssay Description:Displacement of [3H]diprenorphine from human Opioid receptor delta 1 epressing HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Harvard University

Curated by ChEMBL
LigandPNGBDBM50123759((E)-(1S,2S,6R,7R)-7-((S)-1-Carbamoyl-2-phenyl-ethy...)
Affinity DataEC50:  7.90nMAssay Description:Compound tested at 10 uM for the ability to induce Opioid receptor mu 1-mediated binding of [35S]GTP-gamma-S to G proteins in CHO membrane preparatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed