BDBM50123966 (E)-N-(2-Amino-phenyl)-3-[4-(biphenyl-4-ylsulfamoyl)-phenyl]-acrylamide::CHEMBL359303::N-(2-Amino-phenyl)-3-[4-(biphenyl-4-ylsulfamoyl)-phenyl]-acrylamide::US8796330, 160

SMILES Nc1ccccc1NC(=O)\C=C\c1ccc(cc1)S(=O)(=O)Nc1ccc(cc1)-c1ccccc1

InChI Key InChIKey=CSSVMHPMCABDCZ-XDHOZWIPSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50123966   

TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

US Patent
LigandPNGBDBM50123966((E)-N-(2-Amino-phenyl)-3-[4-(biphenyl-4-ylsulfamoy...)
Affinity DataIC50:  1.20E+3nMT: 2°CAssay Description:For deacetylase assays, 20,000 cpm of the [3H]-metabolically labeled acetylated histone substrate (M. Yoshida et al., J. Biol. Chem. 265(28): 17174-1...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

US Patent
LigandPNGBDBM50123966((E)-N-(2-Amino-phenyl)-3-[4-(biphenyl-4-ylsulfamoy...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibitory concentration against human Histone deacetylase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

US Patent
LigandPNGBDBM50123966((E)-N-(2-Amino-phenyl)-3-[4-(biphenyl-4-ylsulfamoy...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibitory activity on partially purified recombinant human Histone deacetylase 1 (HDAC-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed