BDBM50126594 3-Phenyl-4-{4-[3-(pyridin-2-ylamino)-propoxy]-phenyl}-butyric acid::3-phenyl-4-(4-(3-(pyridin-2-ylamino)propoxy)phenyl)butanoic acid::CHEMBL36346

SMILES OC(=O)CC(Cc1ccc(OCCCNc2ccccn2)cc1)c1ccccc1

InChI Key InChIKey=IAMUMIBDQILHMZ-UHFFFAOYSA-N

Data  3 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50126594   

TargetIntegrin alpha-V/beta-5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50126594(3-phenyl-4-(4-(3-(pyridin-2-ylamino)propoxy)phenyl...)
Affinity DataKi:  6nMAssay Description:Binding affinity for alphaV-beta5 vitronectin receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50126594(3-phenyl-4-(4-(3-(pyridin-2-ylamino)propoxy)phenyl...)
Affinity DataIC50: 8nMAssay Description:Inhibition of human integrin alpha-v-beta-3 receptor by solid phase receptor assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50126594(3-phenyl-4-(4-(3-(pyridin-2-ylamino)propoxy)phenyl...)
Affinity DataIC50: 20nMAssay Description:Inhibition of integrin alpha-v-beta-5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50126594(3-phenyl-4-(4-(3-(pyridin-2-ylamino)propoxy)phenyl...)
Affinity DataIC50: 29nMAssay Description:Inhibition of human integrin alpha-v-beta-3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50126594(3-phenyl-4-(4-(3-(pyridin-2-ylamino)propoxy)phenyl...)
Affinity DataKi:  32nMAssay Description:Binding affinity for alphaV-beta3 vitronectin receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50126594(3-phenyl-4-(4-(3-(pyridin-2-ylamino)propoxy)phenyl...)
Affinity DataIC50: 96nMAssay Description:Inhibition of integrin alphavbeta1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50126594(3-phenyl-4-(4-(3-(pyridin-2-ylamino)propoxy)phenyl...)
Affinity DataIC50: 500nMAssay Description:Inhibition of HEK 293 cell adhesion to vitronectin by human alphaV-beta3 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50126594(3-phenyl-4-(4-(3-(pyridin-2-ylamino)propoxy)phenyl...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity for alphaIIb-beta3 vitronectin receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-6(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50126594(3-phenyl-4-(4-(3-(pyridin-2-ylamino)propoxy)phenyl...)
Affinity DataIC50: 1.98E+4nMAssay Description:Inhibition of integrin alpha-beta-6 receptor expressed in HT29 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed