BDBM50127637 5-(2,6-Dichloro-biphenyl-4-ylmethylene)-3-aza-tricyclo[4.4.2.0*3,8*]dodecane-7-carboxylic acid methyl ester::CHEMBL64630

SMILES COC(=O)C1C2CCC3CN2C\C(=C/c2cc(Cl)c(c(Cl)c2)-c2ccccc2)C1CC3

InChI Key

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50127637   

TargetSodium-dependent serotonin transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50127637(5-(2,6-Dichloro-biphenyl-4-ylmethylene)-3-aza-tric...)
Affinity DataKi:  2.77E+3nMAssay Description:Ability to inhibit [3H]5-HT reuptake at serotonin transporter from rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50127637(5-(2,6-Dichloro-biphenyl-4-ylmethylene)-3-aza-tric...)
Affinity DataKi:  8.74E+3nMAssay Description:Ability to inhibit [3H]DA reuptake at dopamine transporter from rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50127637(5-(2,6-Dichloro-biphenyl-4-ylmethylene)-3-aza-tric...)
Affinity DataKi: >1.00E+4nMAssay Description:Ability to inhibit [3H]NE reuptake at norepinephrine transporter from rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed