BDBM50128070 (4''-{[ALLYL(METHYL)AMINO]METHYL}-1,1''-BIPHENYL-4-YL)(4-BROMOPHENYL)METHANONE::CHEMBL481608::CHEMBL65230::{4'-[(Allyl-methyl-amino)-methyl]-biphenyl-4-yl}-(4-bromo-phenyl)-methanone

SMILES C[N@@](CC=C)Cc1ccc(cc1)c2ccc(cc2)C(=O)c3ccc(cc3)Br

InChI Key InChIKey=YATCZCSDJCQNAL-UHFFFAOYSA-N

Data  6 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50128070   

TargetLanosterol synthase(Human)
Centre Hospitalier Universitaire Vaudois (Chuv) and University of Lausanne (Unil

Curated by ChEMBL
LigandPNGBDBM50128070(CHEMBL481608 | CHEMBL65230 | (4''-{[ALLYL(METHYL)A...)
Affinity DataIC50: 8nMAssay Description:Inhibition of human liver microsome 2,3-OSC after 1 hr by Silica gel plate phosphor imagingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
Centre Hospitalier Universitaire Vaudois (Chuv) and University of Lausanne (Unil

Curated by ChEMBL
LigandPNGBDBM50128070(CHEMBL481608 | CHEMBL65230 | (4''-{[ALLYL(METHYL)A...)
Affinity DataIC50: 16nMAssay Description:Inhibitory activity against Oxidosqualene-lanosterol cyclase from human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene--hopene cyclase(Alicyclobacillus acidocaldarius)
Albert-Ludwigs-University of Freiburg

Curated by ChEMBL
LigandPNGBDBM50128070(CHEMBL481608 | CHEMBL65230 | (4''-{[ALLYL(METHYL)A...)
Affinity DataIC50: 29nMAssay Description:Inhibitory activity against squalene hopene cyclase from Alicyclobacillus acidocaldariusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetLanosterol synthase(Human)
Centre Hospitalier Universitaire Vaudois (Chuv) and University of Lausanne (Unil

Curated by ChEMBL
LigandPNGBDBM50128070(CHEMBL481608 | CHEMBL65230 | (4''-{[ALLYL(METHYL)A...)
Affinity DataIC50: 250nMAssay Description:Inhibition of human OSC expressed in Saccharomyces cerevisiae SMY8More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCycloartenol synthase(Mouse-ear cress)
Università

Curated by ChEMBL
LigandPNGBDBM50128070(CHEMBL481608 | CHEMBL65230 | (4''-{[ALLYL(METHYL)A...)
Affinity DataIC50: 250nMAssay Description:Inhibition of Arabidopsis thaliana cycloartenol synthase expressed in Saccharomyces cerevisiae SMY8More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetLanosterol synthase ERG7(Baker's yeast)
Università

Curated by ChEMBL
LigandPNGBDBM50128070(CHEMBL481608 | CHEMBL65230 | (4''-{[ALLYL(METHYL)A...)
Affinity DataIC50: 320nMAssay Description:Inhibition of yeast OSC expressed in Saccharomyces cerevisiae SMY8More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed