BDBM50128642 1-(4-(thiophen-2-yl)benzyl)-N-hydroxy-4-(4-methoxyphenylsulfonyl)piperidine-4-carboxamide::4-(4-Methoxy-benzenesulfonyl)-1-(4-thiophen-2-yl-benzyl)-piperidine-4-carboxylic acid hydroxyamide::CHEMBL80183

SMILES COc1ccc(cc1)S(=O)(=O)C1(CCN(Cc2ccc(cc2)-c2cccs2)CC1)C(=O)NO

InChI Key InChIKey=RHTOEITZKIINCY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50128642   

TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50128642(1-(4-(thiophen-2-yl)benzyl)-N-hydroxy-4-(4-methoxy...)
Affinity DataIC50: 3nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-13.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50128642(1-(4-(thiophen-2-yl)benzyl)-N-hydroxy-4-(4-methoxy...)
Affinity DataIC50: 11nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-9.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
LigandPNGBDBM50128642(1-(4-(thiophen-2-yl)benzyl)-N-hydroxy-4-(4-methoxy...)
Affinity DataIC50: 273nMAssay Description:In vitro inhibitory activity against tumor necrosis factor alpha converting enzyme (TACE).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50128642(1-(4-(thiophen-2-yl)benzyl)-N-hydroxy-4-(4-methoxy...)
Affinity DataIC50: 531nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed