BDBM50128646 4-(4-Methoxy-benzenesulfonyl)-1-phenethyl-piperidine-4-carboxylic acid hydroxyamide::CHEMBL310057::N-hydroxy-4-(4-methoxyphenylsulfonyl)-1-phenethylpiperidine-4-carboxamide

SMILES COc1ccc(cc1)S(=O)(=O)C1(CCN(CCc2ccccc2)CC1)C(=O)NO

InChI Key InChIKey=KASLMAICRUMQME-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50128646   

TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50128646(N-hydroxy-4-(4-methoxyphenylsulfonyl)-1-phenethylp...)
Affinity DataIC50: 9nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-13.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50128646(N-hydroxy-4-(4-methoxyphenylsulfonyl)-1-phenethylp...)
Affinity DataIC50: 45nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-9.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
LigandPNGBDBM50128646(N-hydroxy-4-(4-methoxyphenylsulfonyl)-1-phenethylp...)
Affinity DataIC50: 470nMAssay Description:In vitro inhibitory activity against tumor necrosis factor alpha converting enzyme (TACE).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50128646(N-hydroxy-4-(4-methoxyphenylsulfonyl)-1-phenethylp...)
Affinity DataIC50: 1.31E+3nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed