BDBM50129147 5-Cyclohexylmethylene-9-fluoro-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene::CHEMBL418670

SMILES CC1=CC(C)(C)Nc2ccc3-c4cc(F)ccc4O\C(=C/C4CCCCC4)c3c12

InChI Key InChIKey=JSEOKPFLGWDHHR-QRVIBDJDSA-N

Data  1 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50129147   

TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50129147(5-Cyclohexylmethylene-9-fluoro-2,2,4-trimethyl-2,5...)
Affinity DataKi: >100nMAssay Description:Binding affinity to human progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50129147(5-Cyclohexylmethylene-9-fluoro-2,2,4-trimethyl-2,5...)
Affinity DataIC50:  800nMAssay Description:Inhibitory concentration for antagonistic activity towards human progesterone receptor (hPR) using the cotransfection assay in CV-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50129147(5-Cyclohexylmethylene-9-fluoro-2,2,4-trimethyl-2,5...)
Affinity DataEC50:  48nMAssay Description:Effective concentration for agonist activity towards human progesterone receptor (hPR) using the cotransfection assay in CV-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed