BDBM50129175 9-Fluoro-2,2,4-trimethyl-7-nitro-2,3,4,5-tetrahydro-1H-6-oxa-1-aza-chrysene::CHEMBL65380

SMILES CC1CC(C)(C)Nc2ccc-3c(COc4c-3cc(F)cc4[N+]([O-])=O)c12

InChI Key InChIKey=FLVQAJVWSKGCPZ-UHFFFAOYSA-N

Data  1 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50129175   

TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50129175(9-Fluoro-2,2,4-trimethyl-7-nitro-2,3,4,5-tetrahydr...)
Affinity DataKi:  370nMAssay Description:Binding affinity at human progesterone receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50129175(9-Fluoro-2,2,4-trimethyl-7-nitro-2,3,4,5-tetrahydr...)
Affinity DataIC50: 483nMAssay Description:Inhibition of human progesterone receptor activation in T47D human breast cancer cell.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50129175(9-Fluoro-2,2,4-trimethyl-7-nitro-2,3,4,5-tetrahydr...)
Affinity DataEC50:  781nMAssay Description:Effective concentration for antagonistic activity towards human progesterone in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed