BDBM50131066 2-Oxo-2H-chromene-3-carboxylic acid::CHEMBL83294

SMILES OC(=O)c1cc2ccccc2oc1=O

InChI Key InChIKey=ACMLKANOGIVEPB-UHFFFAOYSA-N

Data  13 KI  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 50131066   

TargetAmine oxidase [flavin-containing] B(Human)
R.C. Patel Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50131066(2-Oxo-2H-chromene-3-carboxylic acid | CHEMBL83294)
Affinity DataIC50: 17nMAssay Description:Inhibition of MAO-B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50131066(2-Oxo-2H-chromene-3-carboxylic acid | CHEMBL83294)
Affinity DataKi:  2.90E+3nMAssay Description:Inhibition of human carbonic anhydrase 12 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 5A, mitochondrial(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50131066(2-Oxo-2H-chromene-3-carboxylic acid | CHEMBL83294)
Affinity DataKi:  4.50E+3nMAssay Description:Inhibition of human carbonic anhydrase 5A by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 7(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50131066(2-Oxo-2H-chromene-3-carboxylic acid | CHEMBL83294)
Affinity DataKi:  6.20E+3nMAssay Description:Inhibition of human carbonic anhydrase 7 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50131066(2-Oxo-2H-chromene-3-carboxylic acid | CHEMBL83294)
Affinity DataKi:  6.50E+3nMAssay Description:Inhibition of human carbonic anhydrase 9 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 3(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50131066(2-Oxo-2H-chromene-3-carboxylic acid | CHEMBL83294)
Affinity DataKi:  6.60E+3nMAssay Description:Inhibition of human carbonic anhydrase 3 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 14(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50131066(2-Oxo-2H-chromene-3-carboxylic acid | CHEMBL83294)
Affinity DataKi:  8.20E+3nMAssay Description:Inhibition of human carbonic anhydrase 14 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 15(Mouse)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50131066(2-Oxo-2H-chromene-3-carboxylic acid | CHEMBL83294)
Affinity DataKi:  8.80E+3nMAssay Description:Inhibition of mouse carbonic anhydrase 15 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50131066(2-Oxo-2H-chromene-3-carboxylic acid | CHEMBL83294)
Affinity DataKi:  9.30E+3nMAssay Description:Inhibition of human carbonic anhydrase 1 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50131066(2-Oxo-2H-chromene-3-carboxylic acid | CHEMBL83294)
Affinity DataKi:  9.70E+3nMAssay Description:Inhibition of human carbonic anhydrase 4 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 13(Mouse)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50131066(2-Oxo-2H-chromene-3-carboxylic acid | CHEMBL83294)
Affinity DataKi:  2.03E+4nMAssay Description:Inhibition of mouse carbonic anhydrase 13 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 5B, mitochondrial(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50131066(2-Oxo-2H-chromene-3-carboxylic acid | CHEMBL83294)
Affinity DataKi:  3.43E+4nMAssay Description:Inhibition of human carbonic anhydrase 5B by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50131066(2-Oxo-2H-chromene-3-carboxylic acid | CHEMBL83294)
Affinity DataKi:  7.63E+4nMAssay Description:Inhibition of human carbonic anhydrase 6 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetG-protein coupled receptor 35(Human)
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50131066(2-Oxo-2H-chromene-3-carboxylic acid | CHEMBL83294)
Affinity DataEC50:  9.23E+4nMAssay Description:Agonist activity at GPR35 in human HT-29 cells by DMR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2020
Entry Details Article
PubMed
TargetG-protein coupled receptor 35(Human)
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50131066(2-Oxo-2H-chromene-3-carboxylic acid | CHEMBL83294)
Affinity DataIC50: 1.00E+5nMAssay Description:Agonist activity at GPR35 in human HT-29 cells assessed as induction of cell desensitization to 1 uM zaprinast preincubated for 1 hr followed by zapr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50131066(2-Oxo-2H-chromene-3-carboxylic acid | CHEMBL83294)
Affinity DataKi: >5.00E+5nMAssay Description:Inhibition of human carbonic anhydrase 2 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Inha University

Curated by ChEMBL
LigandPNGBDBM50131066(2-Oxo-2H-chromene-3-carboxylic acid | CHEMBL83294)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human Protein-tyrosine phosphatase 1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed