BDBM50131631 CHEMBL331278::[1-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-1H-imidazol-2-yl]-phenyl-methanone

SMILES CS(=O)(=O)c1ccc(cc1)-c1cnc(C(=O)c2ccccc2)n1-c1ccc(F)cc1

InChI Key InChIKey=PFDLSVYYAZJPGK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50131631   

TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Domp&Egrove

Curated by ChEMBL
LigandPNGBDBM50131631(CHEMBL331278 | [1-(4-Fluoro-phenyl)-5-(4-methanesu...)
Affinity DataIC50:  30nMAssay Description:In vitro percent inhibition of Prostaglandin G/H synthase 2 (COX-2) in human whole blood was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Domp&Egrove

Curated by ChEMBL
LigandPNGBDBM50131631(CHEMBL331278 | [1-(4-Fluoro-phenyl)-5-(4-methanesu...)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro inhibitory activity against human Prostaglandin G/H synthase 1 (COX-1) in U-937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed