BDBM50132153 (2,4-Dichloro-5-methoxy-phenyl)-[7-methoxy-8-(2-methoxy-ethoxy)-4a,5,10,10a-tetrahydro-pyrimido[4,5-b]quinolin-4-yl]-amine::CHEMBL100551

SMILES COCCOc1cc2Nc3ncnc(Nc4cc(OC)c(Cl)cc4Cl)c3Cc2cc1OC

InChI Key InChIKey=XMAKXDZNYHCNHY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50132153   

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50132153((2,4-Dichloro-5-methoxy-phenyl)-[7-methoxy-8-(2-me...)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of Src protein tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50132153((2,4-Dichloro-5-methoxy-phenyl)-[7-methoxy-8-(2-me...)
Affinity DataIC50: 28nMAssay Description:Inhibition of Src protein tyrosine kinase dependent cellular proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Fyn(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50132153((2,4-Dichloro-5-methoxy-phenyl)-[7-methoxy-8-(2-me...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Fyn dependent cellular proliferation of rat 2 fibroblast cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed