BDBM50132154 (2,4-Dichloro-phenyl)-[7-methoxy-8-(2-methoxy-ethoxy)-4a,5,10,10a-tetrahydro-pyrimido[4,5-b]quinolin-4-yl]-amine::CHEMBL322689

SMILES COCCOc1cc2Nc3ncnc(Nc4ccc(Cl)cc4Cl)c3Cc2cc1OC

InChI Key InChIKey=KSKVKJBGARBSTO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50132154   

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50132154((2,4-Dichloro-phenyl)-[7-methoxy-8-(2-methoxy-etho...)
Affinity DataIC50: 120nMAssay Description:Inhibition of Src protein tyrosine kinase dependent cellular proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50132154((2,4-Dichloro-phenyl)-[7-methoxy-8-(2-methoxy-etho...)
Affinity DataIC50: 120nMAssay Description:Inhibition of Src protein tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed