BDBM50133048 CHEMBL429351::Opioid Peptide [d-Ala(8)]Dynorphin derivative

SMILES CC(C)C[C@H](NC(=O)C1(Cc2ccccc2C1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(N)=O

InChI Key InChIKey=HIRORZRJMOACBO-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50133048   

TargetKappa-type opioid receptor(Rat)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50133048(Opioid Peptide [d-Ala(8)]Dynorphin derivative | CH...)
Affinity DataKi:  26.5nMAssay Description:Binding affinity towards rat Opioid receptor kappa 1 expressed in CHO cells of chinese hamster ovary was determined using [3H]diprenorphine as radiol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50133048(Opioid Peptide [d-Ala(8)]Dynorphin derivative | CH...)
Affinity DataKi:  364nMAssay Description:Binding affinity towards rat Opioid receptor mu 1 expressed in CHO cells of chinese hamster ovary was determined using [3H]DAMGOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50133048(Opioid Peptide [d-Ala(8)]Dynorphin derivative | CH...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity towards mouse Opioid receptor delta 1 expressed in CHO cells of chinese hamster ovary was determined using [3H]-DPDGE as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed