BDBM50134994 (2-(2-hydroxy-3-(4-hydroxy-4-phenylpiperidin-1-yl)propoxy)phenyl)(phenyl)methanone::CHEMBL148260::{2-[2-Hydroxy-3-(4-hydroxy-4-phenyl-piperidin-1-yl)-propoxy]-phenyl}-phenyl-methanone

SMILES OC(COc1ccccc1C(=O)c1ccccc1)CN1CCC(O)(CC1)c1ccccc1

InChI Key InChIKey=KNWQIFLHCZAXAN-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50134994   

TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
University Of Vienna

Curated by ChEMBL
LigandPNGBDBM50134994((2-(2-hydroxy-3-(4-hydroxy-4-phenylpiperidin-1-yl)...)
Affinity DataIC50:  310nMAssay Description:Inhibition of P-glycoprotein-mediated daunorubicin efflux from human CCRF-CEM/VCR1000 cells after 240 secs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
University Of Vienna

Curated by ChEMBL
LigandPNGBDBM50134994((2-(2-hydroxy-3-(4-hydroxy-4-phenylpiperidin-1-yl)...)
Affinity DataEC50:  307nMAssay Description:Inhibition of P-glycoprotein expressed in MDR CCRF vcr1000 cells by daunorubicin efflux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed