BDBM50135821 (Bis-phosphono-methyl)-cycloheptyl-ammonium::(Cycloheptylamino-phosphono-methyl)-phosphonic acid::(cycloheptylamino)methylenediphosphonic acid::(cyloheptylamino)methylene-1,1-bisphosphonate::CHEMBL53950::Incadronic acid

SMILES OP(O)(O)C(=NC1CCCCCC1)P(O)(O)=O

InChI Key InChIKey=SPRXFVYNBMUPLY-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50135821   

TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50135821((Bis-phosphono-methyl)-cycloheptyl-ammonium | (Cyc...)
Affinity DataKi:  22nMAssay Description:Binding affinity towards farnesyl Pyrophosphate Synthase using [14C]- isopentenyl pyrophosphate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50135821((Bis-phosphono-methyl)-cycloheptyl-ammonium | (Cyc...)
Affinity DataIC50:  229nMAssay Description:Inhibitory activity against farnesyl Pyrophosphate Synthase expressed as #NAME? (M)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetH(+)-exporting diphosphatase(Trypanosoma brucei)
University Of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50135821((Bis-phosphono-methyl)-cycloheptyl-ammonium | (Cyc...)
Affinity DataIC50:  4.43E+4nMAssay Description:Inhibition of recombinant Trypanosoma brucei soluble vacuolar pyrophosphatase expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50135821((Bis-phosphono-methyl)-cycloheptyl-ammonium | (Cyc...)
Affinity DataIC50:  30nMAssay Description:Inhibition of recombinant human FPPS expressed in Escherichia coli by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50135821((Bis-phosphono-methyl)-cycloheptyl-ammonium | (Cyc...)
Affinity DataIC50:  230nMAssay Description:Inhibitory activity against farnesyl Pyrophosphate Synthase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed