BDBM50136180 4-(4-Amino-phenoxy)-1-[1-(4-fluoro-phenyl)-piperidin-4-yl]-4-phenyl-butan-1-one::CHEMBL423034

SMILES Nc1ccc(OC(CCC(=O)C2CCN(CC2)c2ccc(F)cc2)c2ccccc2)cc1

InChI Key InChIKey=LKDDUCONRFBZBT-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50136180   

Target5-hydroxytryptamine receptor 2A(Rat)
Faes Farma

Curated by ChEMBL
LigandPNGBDBM50136180(4-(4-Amino-phenoxy)-1-[1-(4-fluoro-phenyl)-piperid...)
Affinity DataKi:  16.4nMAssay Description:Binding affinity against 5-hydroxytryptamine 2A receptor by displacement of [3H]ketanserin from rat prefrontal cerebral cortex mambranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Faes Farma

Curated by ChEMBL
LigandPNGBDBM50136180(4-(4-Amino-phenoxy)-1-[1-(4-fluoro-phenyl)-piperid...)
Affinity DataKi:  108nMAssay Description:Displacement of [3H]8-OH-DPAT from 5-hydroxytryptamine 1A receptor of rat hippocampus mambranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Faes Farma

Curated by ChEMBL
LigandPNGBDBM50136180(4-(4-Amino-phenoxy)-1-[1-(4-fluoro-phenyl)-piperid...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity against serotonin transporter (SERT) by displacement of [3H]paroxetine in male wistar ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed