BDBM50138239 4-[2-(4-Imidazol-1-yl-phenoxy)-ethyl]-piperazine-1-carboxylic acid ethyl ester::CHEMBL114555

SMILES CCOC(=O)N1CCN(CCOc2ccc(cc2)-n2ccnc2)CC1

InChI Key InChIKey=GGPFRXPJXXCZQB-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50138239   

TargetCytochrome P450 2C19(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50138239(4-[2-(4-Imidazol-1-yl-phenoxy)-ethyl]-piperazine-1...)
Affinity DataIC50: 469nMAssay Description:Inhibition of cytochrome P450 2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50138239(4-[2-(4-Imidazol-1-yl-phenoxy)-ethyl]-piperazine-1...)
Affinity DataIC50: 1.44E+3nMAssay Description:Inhibition of cytochrome P450 2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50138239(4-[2-(4-Imidazol-1-yl-phenoxy)-ethyl]-piperazine-1...)
Affinity DataIC50: 2.24E+3nMAssay Description:Inhibition of cytochrome P450 1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50138239(4-[2-(4-Imidazol-1-yl-phenoxy)-ethyl]-piperazine-1...)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of cytochrome P450 2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50138239(4-[2-(4-Imidazol-1-yl-phenoxy)-ethyl]-piperazine-1...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of cytochrome P450 3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed