BDBM50138977 CHEMBL419740::N-(3-Aminomethyl-phenyl)-acetamidin::N-(3-Aminomethyl-phenyl)-acetamidine

SMILES CC(=N)Nc1cccc(CN)c1

InChI Key InChIKey=XPQAJKGBNGGGQF-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50138977   

TargetNitric oxide synthase, brain(Homo sapiens (Human))
Instituto De QuíMica MéDica

Curated by ChEMBL
LigandPNGBDBM50138977(CHEMBL419740 | N-(3-Aminomethyl-phenyl)-acetamidin...)
Affinity DataKi:  40nMAssay Description:Inhibition of nNOS (unknown origin) assessed as conversion of L-[3H]arginine to L-[3H]citrullineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50138977(CHEMBL419740 | N-(3-Aminomethyl-phenyl)-acetamidin...)
Affinity DataIC50:  480nMAssay Description:Inhibitory activity against endothelial nitric oxide synthase (eNOS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Instituto De QuíMica MéDica

Curated by ChEMBL
LigandPNGBDBM50138977(CHEMBL419740 | N-(3-Aminomethyl-phenyl)-acetamidin...)
Affinity DataIC50:  40nMAssay Description:Inhibition of human nNOSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50138977(CHEMBL419740 | N-(3-Aminomethyl-phenyl)-acetamidin...)
Affinity DataIC50:  11nMAssay Description:Inhibitory activity against neuronal nitric oxide synthase (nNOS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed