BDBM50139407 4-{2-[2-((2R,6S)-2,6-Dimethyl-piperidin-1-yl)-ethyl]-benzofuran-5-yl}-benzonitrile::CHEMBL162591

SMILES C[C@H]1CCC[C@@H](C)N1CCc1cc2cc(ccc2o1)-c1ccc(cc1)C#N

InChI Key InChIKey=DCIRDTIBHJXEGG-HDICACEKSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50139407   

TargetHistamine H3 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50139407(4-{2-[2-((2R,6S)-2,6-Dimethyl-piperidin-1-yl)-ethy...)
Affinity DataKi:  2.40nMAssay Description:Binding potency was determined by displacement of [3H]-N-alpha-methyl histamine from cloned human histamine H3 receptor expressed in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50139407(4-{2-[2-((2R,6S)-2,6-Dimethyl-piperidin-1-yl)-ethy...)
Affinity DataKi:  2.40nMAssay Description:Binding potency was determined by displacement of [3H]N-alpha-methyl histamine from cloned human histamine H3 receptor expressed in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50139407(4-{2-[2-((2R,6S)-2,6-Dimethyl-piperidin-1-yl)-ethy...)
Affinity DataKi:  21nMAssay Description:Binding potency was determined by displacement of [3H]-N-alpha-methyl histamine from histamine H3 receptor of rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50139407(4-{2-[2-((2R,6S)-2,6-Dimethyl-piperidin-1-yl)-ethy...)
Affinity DataKi:  22nMAssay Description:Binding potency was determined by displacement of [3H]N-alpha-methyl histamine from histamine H3 receptor of rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed