BDBM50139451 CHEMBL3765747

SMILES Cc1ccc(cc1C)S(=O)(=O)c1cnc2ccccc2c1N1CCOCC1

InChI Key InChIKey=HDVXJJUOYDLALI-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50139451   

TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50139451(CHEMBL3765747)
Affinity DataKi:  52nMAssay Description:Displacement of [3H]MPEP from recombinant human mGluR5a expressed in A18 cells measured after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50139451(CHEMBL3765747)
Affinity DataKi:  52nMAssay Description:Displacement of [3H]M-MPEP from recombinant human mGluR5a expressed in human A18 cell membrane homogenate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50139451(CHEMBL3765747)
Affinity DataKi:  52nMAssay Description:Displacement of [3H]M-MPEP from recombinant human mGluR5a expressed in human A18 cell membrane homogenate measured after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50139451(CHEMBL3765747)
Affinity DataKi:  68nMAssay Description:Displacement of [3H]M-MPEP from mGluR5 in rat cerebrocortical membranes measured after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50139451(CHEMBL3765747)
Affinity DataKi:  68nMAssay Description:Displacement of [3H]MPEP from rat mGlu5 receptor expressed in rat cerebrocortical membrane measured after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50139451(CHEMBL3765747)
Affinity DataKi:  68nMAssay Description:Displacement of [3H]M-MPEP from mGluR5 in Sprague-Dawley rat cerebrocortical membranes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed