BDBM50139850 CHEMBL3763418::US10577361, E4
SMILES Cc1ncoc1-c1nnc(SCCCCN2CCOC(C2)c2ccc(cc2)C(F)(F)F)n1C
InChI Key InChIKey=WMFCPIPAGHYFMC-UHFFFAOYSA-N
Data 11 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50139850
Affinity DataKi: 25nMAssay Description:Antagonist activity at human dopamine D3 receptor expressed in CHO cells after 90 mins by [35S]-GTPgamma S assayMore data for this Ligand-Target Pair
Affinity DataKi: 25.1nMAssay Description:Displacement of [125I]-7-OH-PIPAT from rat brain dopamine D2 receptor after 45 mins by microplate scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 79nMAssay Description:Agonist activity at human dopamine D3 receptor expressed in CHO cells after 90 mins by [35S]-GTPgamma S assayMore data for this Ligand-Target Pair
Affinity DataKi: 79nMAssay Description:Displacement of [125I]-7-OH-PIPAT from rat brain dopamine D3 receptor after 45 mins by microplate scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 89.1nMAssay Description:[3H]-Spiperone Binding Assay at hD3 and hD4 recombinant receptors CHO cells transiently transfected with human dopamine type 3 or 4 receptors (CHO-hD...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Aptuit
Curated by ChEMBL
Aptuit
Curated by ChEMBL
Affinity DataKi: 2.51E+3nMAssay Description:Antagonist activity at human dopamine D3 receptor expressed in CHO cells after 90 mins by [35S]-GTPgamma S assayMore data for this Ligand-Target Pair
Affinity DataKi: <1.00E+4nMAssay Description:Agonist activity at human dopamine D3 receptor expressed in CHO cells after 90 mins by [35S]-GTPgamma S assayMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:CHO cells stably expressing human dopamine receptor type 2, long variant (hD2L), coupled to Gα16 protein (CHO-Gα16-hD2L) were seeded into b...More data for this Ligand-Target Pair
Affinity DataKi: <1.00E+4nMAssay Description:Displacement of [3H]-dofetilide from human ERG potassium channel by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: <1.00E+4nMAssay Description:Antagonist activity at human dopamine D3 receptor expressed in CHO cells after 90 mins by [35S]-GTPgamma S assayMore data for this Ligand-Target Pair
Affinity DataKi: <1.00E+4nMAssay Description:Displacement of [125I]-7-OH-PIPAT from rat brain dopamine D2 receptor after 45 mins by microplate scintillation counting analysisMore data for this Ligand-Target Pair