BDBM50139862 3-(4-Hydroxy-phenyl)-chroman-6,7-diol::4',6,7-trihydroxyisoflavan::CHEMBL8328::HIR-1

SMILES Oc1ccc(cc1)C1COc2cc(O)c(O)cc2C1

InChI Key InChIKey=NLIIKGCVOJPMQB-UHFFFAOYSA-N

Data  5 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50139862   

TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Homo sapiens (Human))
Universidad De Santiago

LigandPNGBDBM50139862(3-(4-Hydroxy-phenyl)-chroman-6,7-diol | 4',6,7-tri...)
Affinity DataIC50:  7.10E+4nMpH: 7.3 T: 2°CAssay Description:The reactions were done in a volume of 2 mL and constantly stirred using a magnetic stir bar at room temperature (23 °C). Reactions with the crude, a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Universidad De Santiago

LigandPNGBDBM50139862(3-(4-Hydroxy-phenyl)-chroman-6,7-diol | 4',6,7-tri...)
Affinity DataIC50:  300nMpH: 7.3 T: 2°CAssay Description:The reactions were done in a volume of 2 mL and constantly stirred using a magnetic stir bar at room temperature (23 °C). Reactions with the crude, a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Ovis aries)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50139862(3-(4-Hydroxy-phenyl)-chroman-6,7-diol | 4',6,7-tri...)
Affinity DataKd:  1.10E+4nMAssay Description:Displacement of [3H]-estradiol (E2) from sheep uterine estrogen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Homo sapiens (Human))
Universidad De Santiago De Chile

Curated by ChEMBL
LigandPNGBDBM50139862(3-(4-Hydroxy-phenyl)-chroman-6,7-diol | 4',6,7-tri...)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of 12-hLOMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Universidad De Santiago De Chile

Curated by ChEMBL
LigandPNGBDBM50139862(3-(4-Hydroxy-phenyl)-chroman-6,7-diol | 4',6,7-tri...)
Affinity DataIC50:  510nMAssay Description:Inhibition of 15-hLO1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Homo sapiens (Human))
Universidad De Santiago

LigandPNGBDBM50139862(3-(4-Hydroxy-phenyl)-chroman-6,7-diol | 4',6,7-tri...)
Affinity DataIC50:  7.10E+4nMAssay Description:Inhibition of 15-hLO2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed