BDBM50140143 CHEBI:8227::PINOSYLVIN METHYL ETHER::US11866416, Example 6

SMILES COc1cc(O)cc(\C=C\c2ccccc2)c1

InChI Key InChIKey=JVIXPWIEOVZVJC-UHFFFAOYSA-N

Data  6 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50140143   

TargetTransient receptor potential cation channel subfamily A member 1(Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50140143(CHEBI:8227 | PINOSYLVIN METHYL ETHER | US11866416,...)
Affinity DataEC50:  3.50E+3nMAssay Description:Agonist activity at rat TRPA1 expressed in HEK293 cells assessed as induction of intracellular calcium levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2017
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily A member 1(Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50140143(CHEBI:8227 | PINOSYLVIN METHYL ETHER | US11866416,...)
Affinity DataIC50: 6.90E+3nMAssay Description:Antagonist activity at rat TRPA1 expressed in HEK293 cells assessed as inhibition of allyl isothiocyanate-induced increase of intracellular calcium l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2017
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50140143(CHEBI:8227 | PINOSYLVIN METHYL ETHER | US11866416,...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced increase of intracellular calcium levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2017
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50140143(CHEBI:8227 | PINOSYLVIN METHYL ETHER | US11866416,...)
Affinity DataIC50: 1.50E+4nMAssay Description:Antagonist activity at human TRPV1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2017
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50140143(CHEBI:8227 | PINOSYLVIN METHYL ETHER | US11866416,...)
Affinity DataIC50: 2.37E+4nMAssay Description:Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced increase of intracellular calcium levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2017
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50140143(CHEBI:8227 | PINOSYLVIN METHYL ETHER | US11866416,...)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at TRPV1 (unknown origin) in DRG neuronsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2017
Entry Details Article
PubMed
TargetBiofilm regulatory protein A(Streptococcus mutans serotype c (strain ATCC 70061...)
Uab Research Foundation

US Patent
LigandPNGBDBM50140143(CHEBI:8227 | PINOSYLVIN METHYL ETHER | US11866416,...)
Affinity DataIC50: 4.77E+5nMAssay Description:A previously reported zymographic assay was utilized for the investigation of Gtf enzymatic activity, as described in Example 1. A 1:100 in fresh 5 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2024
Entry Details
US Patent