BDBM50143113 6-Phenethyloxy-3-phenyl-[1,2,4]triazolo[3,4-a]phthalazine::CHEMBL54211

SMILES C(Cc1ccccc1)Oc1nn2c(nnc2c2ccccc12)-c1ccccc1

InChI Key InChIKey=GDQHTINQBXUUJK-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50143113   

TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50143113(6-Phenethyloxy-3-phenyl-[1,2,4]triazolo[3,4-a]phth...)
Affinity DataKi:  380nMAssay Description:Binding affinity for human GABA-A receptor alpha-4-beta-3-gamma-2 subunits in L(tk-) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50143113(6-Phenethyloxy-3-phenyl-[1,2,4]triazolo[3,4-a]phth...)
Affinity DataKi:  720nMAssay Description:Binding affinity for human GABA-A receptor alpha-3-beta-3-gamma-2 subunits in L(tk-) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50143113(6-Phenethyloxy-3-phenyl-[1,2,4]triazolo[3,4-a]phth...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity for human GABA-A receptor alpha-5-beta-3-gamma-2 subunits in L(tk-) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-2/beta-3/gamma-2(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50143113(6-Phenethyloxy-3-phenyl-[1,2,4]triazolo[3,4-a]phth...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity for human GABA-A receptor alpha-2-beta-3-gamma-2 subunits in L(tk-) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed