BDBM50143183 CHEMBL3759179

SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@@H]1CCCCNC(=O)C[C@H](NC(=O)[C@@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](Cc2ccccc2)NC1=O)C(N)=O

InChI Key InChIKey=LVBGVSFZIBQZKG-DUQWPARQSA-N

Data  6 KI  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50143183   

TargetMu-type opioid receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50143183(CHEMBL3759179)
Affinity DataKi:  0.440nMAssay Description:Displacement of [3H]DAMGO from Wistar rat brain membrane MOPMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50143183(CHEMBL3759179)
Affinity DataKi:  0.440nMAssay Description:Displacement of [3H]DAMGO from MOR in Wistar rat brain homogenates by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50143183(CHEMBL3759179)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]-norBNI from Wistar rat brain membrane KOPMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Medical University Of Lodz

Curated by ChEMBL
LigandPNGBDBM50143183(CHEMBL3759179)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]nor-BNI from KOR in Dunkin Hartley guinea pig brain homogenates by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Medical University Of Lodz

Curated by ChEMBL
LigandPNGBDBM50143183(CHEMBL3759179)
Affinity DataKi:  110nMAssay Description:Displacement of [3H][Ile5,6]deltorphin-2 from DOR in Wistar rat brain homogenates by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Medical University Of Lodz

Curated by ChEMBL
LigandPNGBDBM50143183(CHEMBL3759179)
Affinity DataKi:  110nMAssay Description:Displacement of [3H]-[Ile5,6]-deltorphin-2 from Wistar rat brain membrane DOPMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Medical University Of Lodz

Curated by ChEMBL
LigandPNGBDBM50143183(CHEMBL3759179)
Affinity DataEC50:  3.60nMAssay Description:Agonist activity at human recombinant MOR expressed in CHO cells assessed as calcium mobilization by Fluo-4 AM based fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Medical University Of Lodz

Curated by ChEMBL
LigandPNGBDBM50143183(CHEMBL3759179)
Affinity DataEC50:  3.60nMAssay Description:Agonist activity at human recombinant MOP expressed in CHO cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Medical University Of Lodz

Curated by ChEMBL
LigandPNGBDBM50143183(CHEMBL3759179)
Affinity DataEC50:  54nMAssay Description:Agonist activity at human recombinant DOR expressed in CHO cells assessed as calcium mobilization by Fluo-4 AM based fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Medical University Of Lodz

Curated by ChEMBL
LigandPNGBDBM50143183(CHEMBL3759179)
Affinity DataEC50:  102nMAssay Description:Agonist activity at human recombinant KOR expressed in CHO cells assessed as calcium mobilization by Fluo-4 AM based fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed