BDBM50143486 CHEMBL366422::N-Acetyl-4-[4-(4-methanesulfonyl-phenyl)-5-oxo-2,5-dihydro-furan-3-yl]-benzenesulfonamide

SMILES CC(=O)NS(=O)(=O)c1ccc(cc1)C1=C(C(=O)OC1)c1ccc(cc1)S(C)(=O)=O

InChI Key InChIKey=BRCUVPAXYQULRV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50143486   

TargetProstaglandin G/H synthase 2(Sheep)
Jamia Hamdard

Curated by ChEMBL
LigandPNGBDBM50143486(N-Acetyl-4-[4-(4-methanesulfonyl-phenyl)-5-oxo-2,5...)
Affinity DataIC50: 50nMAssay Description:Inhibition of ovine COX2 assessed as reduction in PGF2alpha production incubated for 15 mins by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50143486(N-Acetyl-4-[4-(4-methanesulfonyl-phenyl)-5-oxo-2,5...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory activity against prostaglandin G/H synthase 1 from ovineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Jamia Hamdard

Curated by ChEMBL
LigandPNGBDBM50143486(N-Acetyl-4-[4-(4-methanesulfonyl-phenyl)-5-oxo-2,5...)
Affinity DataIC50: 50nMAssay Description:In vitro inhibitory activity against prostaglandin G/H synthase 2 from ovineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed