BDBM50144206 (1S,2R,5S)-5-(6-Amino-purin-9-yl)-4-fluoro-3-hydroxymethyl-cyclopent-3-ene-1,2-diol::5-(6-Amino-purin-9-yl)-4-fluoro-3-hydroxymethyl-cyclopent-3-ene-1,2-diol::CHEMBL64718

SMILES Nc1ncnc2n(cnc12)[C@H]1[C@H](O)[C@H](O)C(CO)=C1F

InChI Key InChIKey=RWUXFWACUXDNKY-HLTSFMKQSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50144206   

TargetAdenosylhomocysteinase(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50144206((1S,2R,5S)-5-(6-Amino-purin-9-yl)-4-fluoro-3-hydro...)
Affinity DataIC50:  470nMAssay Description:In vitro inhibitory activity of the compound against recombinant S-adenosyl-L-homocysteine hydrolase obtained from human placentaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosylhomocysteinase(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50144206((1S,2R,5S)-5-(6-Amino-purin-9-yl)-4-fluoro-3-hydro...)
Affinity DataIC50:  480nMAssay Description:Inhibition of human placental AdoHcy hydrolase expressed in Escherichia coli JM109More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosylhomocysteinase(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50144206((1S,2R,5S)-5-(6-Amino-purin-9-yl)-4-fluoro-3-hydro...)
Affinity DataIC50:  240nMAssay Description:Inhibition of recombinant human placental AdoHcy hydrolase expressed in Escherichia coli BL21 using AdoHcy as substrate preincubated for 10 mins foll...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosylhomocysteinase(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50144206((1S,2R,5S)-5-(6-Amino-purin-9-yl)-4-fluoro-3-hydro...)
Affinity DataIC50:  480nMAssay Description:Inhibitory activity against enzyme S-adenosylhomocysteine hydrolase of human placentaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed