BDBM50144621 CHEMBL73148::CMI-977::N-(4-{(2S,5S)-5-[(4-fluorophenoxy)methyl]tetrahydrofuran-2-yl}but-3-ynyl)-N-hydroxyurea

SMILES NC(=O)N(O)CCC#C[C@@H]1CC[C@@H](COc2ccc(F)cc2)O1

InChI Key InChIKey=YANONWCPCKIWEC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50144621   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50144621(N-(4-{(2S,5S)-5-[(4-fluorophenoxy)methyl]tetrahydr...)
Affinity DataIC50: 117nMAssay Description:Inhibition constant against arachidonate 5-lipoxygenase More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50144621(N-(4-{(2S,5S)-5-[(4-fluorophenoxy)methyl]tetrahydr...)
Affinity DataIC50: 117nMAssay Description:In vitro inhibitory activity against 5-lipoxygenase in a human whole blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed