BDBM50144622 CHEMBL312082::[3-(5-{4-[(R)-(4-Chloro-phenyl)-phenyl-methyl]-piperazin-1-ylmethyl}-furan-2-yl)-1-methyl-prop-2-ynyl]-N-hydroxyurea

SMILES CC(C#Cc1ccc(CN2CCN(CC2)[C@H](c2ccccc2)c2ccc(Cl)cc2)o1)N(O)C(N)=O

InChI Key InChIKey=FJXRDARXFNFHEP-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50144622   

TargetHistamine H1 receptor(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50144622([3-(5-{4-[(R)-(4-Chloro-phenyl)-phenyl-methyl]-pip...)
Affinity DataKi:  190nMAssay Description:In vitro binding affinity towards histamine H1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50144622([3-(5-{4-[(R)-(4-Chloro-phenyl)-phenyl-methyl]-pip...)
Affinity DataIC50: 3.50E+3nMAssay Description:In vitro inhibitory activity against 5-lipoxygenase in a human whole blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed