BDBM50144626 CHEMBL305662::[4-((2S,5S)-5-{4-[(R)-(4-Chloro-phenyl)-phenyl-methyl]-piperazin-1-ylmethyl}-tetrahydro-furan-2-yl)-but-3-ynyl]-N-hydroxyurea

SMILES NC(=O)N(O)CCC#C[C@@H]1CC[C@@H](CN2CCN(CC2)[C@H](c2ccccc2)c2ccc(Cl)cc2)O1

InChI Key InChIKey=ZBUWQTCXTJMDCD-UODIDJSMSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50144626   

TargetHistamine H1 receptor(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50144626(CHEMBL305662 | [4-((2S,5S)-5-{4-[(R)-(4-Chloro-phe...)
Affinity DataKi:  50nMAssay Description:In vitro binding affinity towards histamine H1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50144626(CHEMBL305662 | [4-((2S,5S)-5-{4-[(R)-(4-Chloro-phe...)
Affinity DataIC50:  310nMAssay Description:In vitro inhibitory activity against 5-lipoxygenase in a human whole blood assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed