BDBM50146808 CHEMBL318664::[(1-ethylpropyl)amino]carbonylphosphonic acid

SMILES CCC(CC)NC(=O)P(O)(O)=O

InChI Key InChIKey=NBDIMGROXSSYHE-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50146808   

Target72 kDa type IV collagenase(Homo sapiens (Human))
The Hebrew University Of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50146808(CHEMBL318664 | [(1-ethylpropyl)amino]carbonylphosp...)
Affinity DataIC50:  3.00E+3nMAssay Description:In vitro inhibitory activity against recombinant matrix metalloprotease-2 was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
The Hebrew University Of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50146808(CHEMBL318664 | [(1-ethylpropyl)amino]carbonylphosp...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibitory activity against recombinant matrix metalloprotease-3 was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
The Hebrew University Of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50146808(CHEMBL318664 | [(1-ethylpropyl)amino]carbonylphosp...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibitory activity against recombinant matrix metalloprotease-9 was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
The Hebrew University Of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50146808(CHEMBL318664 | [(1-ethylpropyl)amino]carbonylphosp...)
Affinity DataIC50:  8.00E+4nMAssay Description:In vitro inhibitory activity against recombinant matrix metalloprotease-1 was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
The Hebrew University Of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50146808(CHEMBL318664 | [(1-ethylpropyl)amino]carbonylphosp...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
The Hebrew University Of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50146808(CHEMBL318664 | [(1-ethylpropyl)amino]carbonylphosp...)
Affinity DataIC50:  4.65E+3nMAssay Description:Inhibition of human Carbonic anhydrase 12-mediated CO2 hydration by stopped-flow methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
The Hebrew University Of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50146808(CHEMBL318664 | [(1-ethylpropyl)amino]carbonylphosp...)
Affinity DataIC50:  8.26E+3nMAssay Description:Inhibition of human Carbonic anhydrase 9-mediated CO2 hydration by stopped-flow methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
The Hebrew University Of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50146808(CHEMBL318664 | [(1-ethylpropyl)amino]carbonylphosp...)
Affinity DataIC50:  8.79E+3nMAssay Description:Inhibition of human Carbonic anhydrase 2-mediated CO2 hydration by stopped-flow methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
The Hebrew University Of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50146808(CHEMBL318664 | [(1-ethylpropyl)amino]carbonylphosp...)
Affinity DataIC50:  6.71E+3nMAssay Description:Inhibition of human Carbonic anhydrase 1-mediated CO2 hydration by stopped-flow methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
The Hebrew University Of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50146808(CHEMBL318664 | [(1-ethylpropyl)amino]carbonylphosp...)
Affinity DataIC50:  1.00E+4nMAssay Description:In vitro inhibitory activity against recombinant matrix metalloprotease-8 was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed