BDBM50146816 (cyclopentylamino)carbonylphosphonic acid::CHEMBL316997

SMILES OP(O)(=O)C(=O)NC1CCCC1

InChI Key InChIKey=CYCCYWRSDZSMIF-UHFFFAOYSA-N

Data  15 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50146816   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
The Hebrew University Of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50146816((cyclopentylamino)carbonylphosphonic acid | CHEMBL...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibitory activity against recombinant matrix metalloprotease-9 was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
The Hebrew University Of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50146816((cyclopentylamino)carbonylphosphonic acid | CHEMBL...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant human MMP-9 using peptide substrate by ELISAMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
The Hebrew University Of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50146816((cyclopentylamino)carbonylphosphonic acid | CHEMBL...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibitory activity against recombinant matrix metalloprotease-8 was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
The Hebrew University Of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50146816((cyclopentylamino)carbonylphosphonic acid | CHEMBL...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibitory activity against recombinant matrix metalloprotease-3 was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
The Hebrew University Of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50146816((cyclopentylamino)carbonylphosphonic acid | CHEMBL...)
Affinity DataIC50:  500nMAssay Description:In vitro inhibitory activity against recombinant matrix metalloprotease-1 was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
The Hebrew University Of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50146816((cyclopentylamino)carbonylphosphonic acid | CHEMBL...)
Affinity DataIC50:  7.26E+3nMAssay Description:Inhibition of human Carbonic anhydrase 12-mediated CO2 hydration by stopped-flow methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
The Hebrew University Of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50146816((cyclopentylamino)carbonylphosphonic acid | CHEMBL...)
Affinity DataIC50:  8.97E+3nMAssay Description:Inhibition of human Carbonic anhydrase 9-mediated CO2 hydration by stopped-flow methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
The Hebrew University Of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50146816((cyclopentylamino)carbonylphosphonic acid | CHEMBL...)
Affinity DataIC50:  7.41E+3nMAssay Description:Inhibition of human Carbonic anhydrase 2-mediated CO2 hydration by stopped-flow methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
The Hebrew University Of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50146816((cyclopentylamino)carbonylphosphonic acid | CHEMBL...)
Affinity DataIC50:  8.79E+3nMAssay Description:Inhibition of human Carbonic anhydrase 1-mediated CO2 hydration by stopped-flow methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
The Hebrew University Of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50146816((cyclopentylamino)carbonylphosphonic acid | CHEMBL...)
Affinity DataIC50:  80nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
The Hebrew University Of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50146816((cyclopentylamino)carbonylphosphonic acid | CHEMBL...)
Affinity DataIC50:  500nMAssay Description:Inhibition of recombinant human MMP-1 using peptide substrate by ELISAMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
The Hebrew University Of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50146816((cyclopentylamino)carbonylphosphonic acid | CHEMBL...)
Affinity DataIC50:  80nMAssay Description:Inhibition of recombinant human MMP-2 using peptide substrate by ELISAMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetStromelysin-1(Homo sapiens (Human))
The Hebrew University Of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50146816((cyclopentylamino)carbonylphosphonic acid | CHEMBL...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant human MMP-3 using peptide substrate by ELISAMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
The Hebrew University Of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50146816((cyclopentylamino)carbonylphosphonic acid | CHEMBL...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant human MMP-8 using peptide substrate by ELISAMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
The Hebrew University Of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50146816((cyclopentylamino)carbonylphosphonic acid | CHEMBL...)
Affinity DataIC50:  80nMAssay Description:In vitro inhibitory activity against recombinant matrix metalloprotease-2 was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed