BDBM50149216 Benzofuran-2-carboxylic acid (2-{4-[benzyl-(2-hydroxycarbamoyl-4,6-dimethyl-phenyl)-sulfamoyl]-phenoxy}-ethyl)-amide::CHEMBL327002::WAY-170523

SMILES Cc1cc(C)c(N(Cc2ccccc2)S(=O)(=O)c2ccc(OCCNC(=O)c3cc4ccccc4o3)cc2)c(c1)C(=O)NO

InChI Key InChIKey=FARMEEAGJWMFSZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50149216   

TargetCollagenase 3(Bos taurus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50149216(Benzofuran-2-carboxylic acid (2-{4-[benzyl-(2-hydr...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibitory concentration against MMP-13 of bovine articular cartilage explantsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149216(Benzofuran-2-carboxylic acid (2-{4-[benzyl-(2-hydr...)
Affinity DataIC50:  17nMAssay Description:Inhibition of Matrix Metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149216(Benzofuran-2-carboxylic acid (2-{4-[benzyl-(2-hydr...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Matrix Metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed