BDBM50150083 CHEMBL338482::[2-(5-Fluoro-2-methoxy-phenoxy)-ethyl]-[2-(1H-indol-3-yl)-ethyl]-amine

SMILES COc1ccc(F)cc1OCCNCCc1c[nH]c2ccccc12

InChI Key InChIKey=PDGNKMACWXAEOS-UHFFFAOYSA-N

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50150083   

TargetSodium-dependent serotonin transporter(Rat)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50150083([2-(5-Fluoro-2-methoxy-phenoxy)-ethyl]-[2-(1H-indo...)
Affinity DataKi:  43nMAssay Description:Binding affinity against serotonin transporter in rat cortical tissues using radioligand [3H]paroxetineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50150083([2-(5-Fluoro-2-methoxy-phenoxy)-ethyl]-[2-(1H-indo...)
Affinity DataKi:  48nMAssay Description:Binding affinity against human 5-hydroxytryptamine 1A receptor in CHO cells labeled with [3H]8-OH-DPAT radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50150083([2-(5-Fluoro-2-methoxy-phenoxy)-ethyl]-[2-(1H-indo...)
Affinity DataIC50: 208nMAssay Description:Inhibition concentration against 5-hydroxytryptamine 1A receptor using cAMP as radioligand in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50150083([2-(5-Fluoro-2-methoxy-phenoxy)-ethyl]-[2-(1H-indo...)
Affinity DataIC50: 208nMAssay Description:Inhibition concentration against binding of radioligand [35S]GTP-gamma-S in CHO cells expressing 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50150083([2-(5-Fluoro-2-methoxy-phenoxy)-ethyl]-[2-(1H-indo...)
Affinity DataIC50: 249nMAssay Description:Inhibition concentration against [3H]5-HT uptake by human serotonin transporter in JAR cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed